ARG44240

anti-FOXA2 / HNF3B antibody

anti-FOXA2 / HNF3B antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody

概述

产品描述 Rabbit Polyclonal antibody recognizes FOXA2 / HNF3B
反应物种 Hu, Ms, Rat
应用 FACS, ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 FOXA2 / HNF3B
抗原物种 Human
抗原 Human FOXA2 / HNF3B recombinant protein (a.a: 139-446)
偶联标记 Un-conjugated
別名 TCF3B; Hepatocyte nuclear factor 3-beta; Forkhead box protein A2; TCF-3B; HNF-3B; HNF3B; Transcription factor 3B; HNF-3-beta

应用说明

应用建议
应用 推荐稀释比
FACS2 - 5 μg / ml
ICC/IF1 - 3 μg / 10^6 cells
IHC-P5 μg / ml
WB0.25 - 0.5 μg / ml
应用说明 The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 15376 Mouse FOXA2

GeneID: 25099 Rat FOXA2

GeneID: 3170 Human FOXA2

背景介绍 This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
研究领域 Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Metabolism antibody
预测分子量 48 kDa
翻译后修饰 Phosphorylation on Thr-156 abolishes binding to target promoters and subsequent transcription activation upon insulin stimulation.

检测图片 (6) Click the Picture to Zoom In

  • ARG44240 anti-FOXA2 / HNF3B antibody IHC-P image

    Immunohistochemistry: Human colonic adenocarcinoma stained with ARG44240 anti-FOXA2 / HNF3B antibody at 2 μg / ml dilution.

  • ARG44240 anti-FOXA2 / HNF3B antibody WB image

    Western blot: HepG2, PC-3 and A549 stained with ARG44240 anti-FOXA2 / HNF3B antibody at 0.5 μg / ml dilution.

  • ARG44240 anti-FOXA2 / HNF3B antibody ICC/IF image

    Immunofluorescence: PC-3 stained with ARG44240 anti-FOXA2 / HNF3B antibody at 5 μg / ml dilution.

  • ARG44240 anti-FOXA2 / HNF3B antibody FACS image

    Flow Cytometry: 293T stained with ARG44240 anti-FOXA2 / HNF3B antibody at 1 μg / 10^6 cells dilution.

  • ARG44240 anti-FOXA2 / HNF3B antibody WB image

    Western blot: Rat pancreas stained with ARG44240 anti-FOXA2 / HNF3B antibody at 0.5 μg / ml dilution.

  • ARG44240 anti-FOXA2 / HNF3B antibody WB image

    Western blot: Mouse pancreas stained with ARG44240 anti-FOXA2 / HNF3B antibody at 0.5 μg / ml dilution.