ARG46408
anti-FLJ14213 antibody
anti-FLJ14213 antibody for Western blot,ICC/IF and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FLJ14213 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FLJ14213 |
| 抗原物种 | Human |
| 抗原 | A 17 amino acid synthetic peptide within the last 50 amino acids of human FLJ14213. |
| 偶联标记 | Un-conjugated |
| 別名 | proline rich 5 like; PRR5L; PROTOR2; PROTOR2; Proline-rich protein 5-like; Protein observed with Rictor-2; Protor-2; FLJ14213 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -458°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRR5L |
| 全名 | proline rich 5 like |
| 背景介绍 | Enables ubiquitin protein ligase binding activity. Involved in several processes, including TORC2 signaling; regulation of fibroblast migration; and regulation of primary metabolic process. Part of TORC2 complex. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Associates with the mTORC2 complex that regulates cellular processes including survival and organization of the cytoskeleton (PubMed:17461779). Regulates the activity of the mTORC2 complex in a substrate-specific manner preventing for instance the specific phosphorylation of PKCs and thereby controlling cell migration (PubMed:22609986). Plays a role in the stimulation of ZFP36-mediated mRNA decay of several ZFP36-associated mRNAs, such as TNF-alpha and GM-CSF, in response to stress (PubMed:21964062). Required for ZFP36 localization to cytoplasmic stress granule (SG) and P-body (PB) in response to stress (PubMed:21964062). [UniProt] |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | Ubl conjugation. [UniProt] |
