ARG45097
anti-FKLF / KLF11 antibody
anti-FKLF / KLF11 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FKLF / KLF11 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FKLF / KLF11 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to amino acids from the N-terminal region of human FKLF protein |
| 偶联标记 | Un-conjugated |
| 別名 | KLF11; KLF Transcription Factor 11; FKLF; Tieg3; MODY7; TIEG2; Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 2; TGFB-Inducible Early Growth Response Protein 2; Krueppel-Like Factor 11; Kruppel Like Factor 11; TIEG-2; TGFB Inducible Early Growth Response 2; FKLF1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.02% NaN3 |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KLF11 |
| 全名 | KLF Transcription Factor 11 |
| 背景介绍 | The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] |
| 生物功能 | Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. [Uniprot] |
| 细胞定位 | Nucleus. [Uniprot] |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
