ARG22263
anti-FKBP51 antibody [Hi51B]
anti-FKBP51 antibody [Hi51B] for ICC/IF,Western blot and Human,Mouse,Rat,Dog,Hamster,Rabbit
概述
| 产品描述 | Mouse Monoclonal antibody [Hi51B] recognizes FKBP51 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Dog, Hm, Rb |
| 应用 | ICC/IF, WB |
| 特异性 | Detects ~51kDa. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | Hi51B |
| 同位型 | IgG |
| 靶点名称 | FKBP51 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide from Human FKBP51 |
| 偶联标记 | Un-conjugated |
| 別名 | HSP90-binding immunophilin; p54; FKBP-51; PPIase FKBP5; FK506-binding protein 5; Ptg-10; Rotamase; FKBP51; FKBP-5; FKBP54; 51 kDa FKBP; 51 kDa FK506-binding protein; EC 5.2.1.8; PPIase; Androgen-regulated protein 6; P54; AIG6; FF1 antigen; Peptidyl-prolyl cis-trans isomerase FKBP5; 54 kDa progesterone receptor-associated immunophilin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.09% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13451 Human Peptidyl-prolyl cis-trans isomerase FKBP5 Swiss-port # Q64378 Mouse Peptidyl-prolyl cis-trans isomerase FKBP5 |
|---|---|
| 基因名称 | FKBP5 |
| 全名 | FK506 binding protein 5 |
| 背景介绍 | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] |
| 生物功能 | Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. [UniProt] |
| 细胞定位 | Cytoplasm, Nucleus |
| 预测分子量 | 51 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG22263 anti-FKBP51 antibody [Hi51B] ICC/IF image
Immunocytochemistry: Mouse MK cells stained with ARG22263 anti-FKBP51 antibody [Hi51B] (red).
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ARG22263 anti-FKBP51 antibody [Hi51B] WB image
Western blot: Human HeLa cell lysates stained with ARG22263 anti-FKBP51 antibody [Hi51B] at 1:1000 dilution.
