ARG44043
anti-FKBP38 antibody
anti-FKBP38 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FKBP38 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FKBP8 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of Human FKBP38/FKBP38/FKBP8 (NP_036313.3). |
| 偶联标记 | Un-conjugated |
| 別名 | FKBP8; FKBP Prolyl Isomerase 8; FKBP38; FKBPr38; Peptidyl-Prolyl Cis-Trans Isomerase FKBP8; FK506 Binding Protein 8, 38kDa; 38 KDa FK506-Binding Protein; FK506-Binding Protein 8; PPIase FKBP8; 38 KDa FKBP; Rotamase; FKBP-38; HFKBP38; FKBP-8; FK506-Binding Protein 8 (38kD); FK506 Binding Protein 8; EC 5.2.1.8; FKBPR38 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FKBP8 |
| 全名 | FKBP Prolyl Isomerase |
| 背景介绍 | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. |
| 生物功能 | Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. Involved in the inhibition of viral infection by influenza A viruses (IAV). |
| 细胞定位 | Membrane, Mitochondrion |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation |
检测图片 (4) Click the Picture to Zoom In
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ARG44043 anti-FKBP38 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG44043 anti-FKBP38 antibody.
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ARG44043 anti-FKBP38 antibody WB image
Western blot: Jurkat, THP1-1, BT-474 and HeLa stained with ARG44043 anti-FKBP38 antibody at 1:1000 dilution.
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ARG44043 anti-FKBP38 antibody WB image
Western blot: Mouse Liver and Mouse Brain stained with ARG44043 anti-FKBP38 antibody at 1:1000 dilution.
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ARG44043 anti-FKBP38 antibody WB image
Western blot: Rat Brain stained with ARG44043 anti-FKBP38 antibody at 1:1000 dilution.
