ARG44663
anti-FH / Fumarase antibody
anti-FH / Fumarase antibody for Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes FH / Fumarase |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | FH / Fumarase |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | FH; Fumarate Hydratase; Fumarase; Fumarate Hydratase, Mitochondrial; EC 4.2.1.2; HsFH; Epididymis Secretory Sperm Binding Protein; HLRCC; MCUL1; FMRD; LRCC; MCL |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FH |
| 全名 | Fumarate Hydratase |
| 背景介绍 | The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008] |
| 生物功能 | Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [UniProt] |
| 细胞定位 | Chromosome, Cytoplasm, Mitochondrion, Nucleus. [UniProt] |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG44663 anti-FH / Fumarase antibody WB image
Western blot: Ramos stained with ARG44663 anti-FH / Fumarase antibody at 1 µg/mL dilution.
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ARG44663 anti-FH / Fumarase antibody IP image
Immunoprecipitation: Ramos lysate immunoprecipitated with 2.5 µg of ARG44663 anti-FH / Fumarase antibody.
