ARG44796
anti-FGFR1 Oncogene Partner antibody
anti-FGFR1 Oncogene Partner antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes FGFR1 Oncogene Partner |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | FGFR1 Oncogene Partner |
| 抗原物种 | Human |
| 抗原表位 | GKKKTSGQKA GDKKANDEAN QSDTSVSLSE PKSKSSLHLL SHETKIGSFL SNRTLDGKDK AGLCPDEDDM EGDSFFDDPI PKPEKTYGLR KEPRKQAGSL |
| 偶联标记 | Un-conjugated |
| 別名 | CEP43; Centrosomal Protein 43; FOP; FGFR1 Oncogene Partner; FGFR1OP; Fibroblast Growth Factor Receptor 1 Oncogene Partner |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CEP43 |
| 全名 | Centrosomal Protein 43 |
| 背景介绍 | This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013] |
| 生物功能 | Required for anchoring microtubules to the centrosomes. [Uniprot] |
| 细胞定位 | Cell projection, Cytoplasm, Cytoskeleton. [Uniprot] |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
-
ARG44796 anti-FGFR1 Oncogene Partner antibody IHC-P image
Immunohistochemistry: Human testis stained with ARG44796 anti-FGFR1 Oncogene Partner antibody at 5 µg/mL dilution.
