ARG44661
anti-FGFBP1 antibody
anti-FGFBP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes FGFBP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | FGFBP1 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | FGFBP1; Fibroblast Growth Factor Binding Protein 1; HBP17; FGFBP; 17 KDa Heparin-Binding Growth Factor-Binding Protein; Fibroblast Growth Factor-Binding Protein 1; 17 KDa HBGF-Binding Protein; FGF-Binding Protein 1; FGF-BP1; FGFBP-1; FGF-BP; Heparin-Binding Growth Factor Binding Protein; HBp17 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q14512 Human Fibroblast growth factor-binding protein 1 |
|---|---|
| 基因名称 | FGFBP1 |
| 全名 | Fibroblast Growth Factor Binding Protein 1 |
| 背景介绍 | This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011] |
| 生物功能 | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. [UniProt] |
| 细胞定位 | Cell membrane, Membrane, Secreted. [UniProt] |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
-
ARG44661 anti-FGFBP1 antibody IHC-P image
Immunohistochemistry: Human Tonsil stained with ARG44661 anti-FGFBP1 antibody at 7.5 µg/mL dilution.
-
ARG44661 anti-FGFBP1 antibody WB image
Western blot: A431 stained with ARG44661 anti-FGFBP1 antibody at 1 µg/mL dilution.
-
ARG44661 anti-FGFBP1 antibody IP image
Immunoprecipitation: A431 lysate immunoprecipitated with 2.5 µg of ARG44661 anti-FGFBP1 antibody.
