ARG41185
anti-FGFBP1 antibody
anti-FGFBP1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FGFBP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FGFBP1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 24-234 of Human FGFBP1 (NP_005121.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Fibroblast growth factor-binding protein 1; 17 kDa heparin-binding growth factor-binding protein; FGF-BP; FGF-binding protein 1; HBp17; FGFBP; 17 kDa HBGF-binding protein; FGFBP-1; HBP17; FGF-BP1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | A549 | ||||
| 实际分子量 | 30 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FGFBP1 |
| 全名 | fibroblast growth factor binding protein 1 |
| 背景介绍 | This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011] |
| 生物功能 | Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. [UniProt] |
| 细胞定位 | Secreted, extracellular space. Cell membrane; Peripheral membrane protein. Note=Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas. [UniProt] |
| 预测分子量 | 26 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41185 anti-FGFBP1 antibody WB image
Western blot: 25 µg of A549 cell lysate stained with ARG41185 anti-FGFBP1 antibody at 1:1000 dilution.
