ARG44659
anti-FGF12 antibody
anti-FGF12 antibody for Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody recognizes FGF12 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | FGF12 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | FGF12; Fibroblast Growth Factor 12; FHF1; Fibroblast Growth Factor Homologous Factor 1; Myocyte-Activating Factor; FGF12B; Fibroblast Growth Factor FGF-12b; Fibroblast Growth Factor 12B; EIEE47; FGF-12; DEE47; FHF-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FGF12 |
| 全名 | Fibroblast Growth Factor 12 |
| 背景介绍 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. [provided by RefSeq, Dec 2019] |
| 生物功能 | Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG44659 anti-FGF12 antibody WB image
Western blot: Human Brain stained with ARG44659 anti-FGF12 antibody at 1 µg/mL dilution.
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ARG44659 anti-FGF12 antibody IP image
Immunoprecipitation: Rat Brain lysate immunoprecipitated with 2.5 µg of ARG44659 anti-FGF12 antibody.
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ARG44659 anti-FGF12 antibody WB image
Western blot: Rat Brain stained with ARG44659 anti-FGF12 antibody at 1 µg/mL dilution.
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ARG44659 anti-FGF12 antibody WB image
Western blot: Mouse Brain stained with ARG44659 anti-FGF12 antibody at 1 µg/mL dilution.
