ARG45886
anti-FGD5 antibody
anti-FGD5 antibody for Western blot,Flow cytometry and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FGD5 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FGD5 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human FGD5. |
| 偶联标记 | Un-conjugated |
| 別名 | FYVE, RhoGEF And PH Domain Containing 5; FGD5; ZFYVE23; FYVE, RhoGEF and PH domain-containing protein 5; Zinc finger FYVE domain-containing protein 23 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 65 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6ZNL6 Human FYVE, RhoGEF and PH domain-containing protein 5 Swiss-port # Q80UZ0 Mouse FYVE, RhoGEF and PH domain-containing protein 5 |
|---|---|
| 基因名称 | FGD5 |
| 全名 | FYVE, RhoGEF And PH Domain Containing 5 |
| 背景介绍 | Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Located in plasma membrane. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape. [UniProt] |
| 细胞定位 | Cell membrane; Cell projection; Cytoplasm; Cytoskeleton; Endoplasmic reticulum; Endosome; Golgi apparatus; Membrane. [UniProt] |
| 预测分子量 | 160 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG45886 anti-FGD5 antibody WB image
Western blot: 293T stained with ARG45886 anti-FGD5 antibody at 0.5 μg/ml dilution.
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ARG45886 anti-FGD5 antibody FACS image
Flow Cytometry: 293T stained with ARG45886 anti-FGD5 antibody at 1 µg/10^6 cells dilution.
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ARG45886 anti-FGD5 antibody WB image
Western blot: Rat lung stained with ARG45886 anti-FGD5 antibody at 0.5 μg/ml dilution.
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ARG45886 anti-FGD5 antibody WB image
Western blot: Mouse lung stained with ARG45886 anti-FGD5 antibody at 0.5 μg/ml dilution.
