ARG44361
anti-FBXO4 antibody
anti-FBXO4 antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FBXO4 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FBXO4 |
| 抗原物种 | Human |
| 抗原 | Human FBXO4 recombinant fusion protein (a.a. sequence: 138-387). |
| 偶联标记 | Un-conjugated |
| 別名 | FBXO4; F-Box Protein 4; FBX4; F-Box Only Protein 4; F-Box Protein Fbx4 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.02% sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FBXO4 |
| 全名 | F-Box Protein 4 |
| 背景介绍 | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| 细胞定位 | Cytoplasm |
| 预测分子量 | 44 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44361 anti-FBXO4 antibody WB image
Western blot: SH-SY5Y stained with ARG44361 anti-FBXO4 antibody at 1:1000 dilution.
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ARG44361 anti-FBXO4 antibody WB image
Western blot: Mouse spleen and Mouse kidney stained with ARG44361 anti-FBXO4 antibody at 1:1000 dilution.
