ARG63516
anti-FAPP2 / PLEKHA8 antibody
anti-FAPP2 / PLEKHA8 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes FAPP2 / PLEKHA8 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FAPP2 / PLEKHA8 |
| 抗原物种 | Human |
| 抗原 | C-DIQTALRNPTENT |
| 偶联标记 | Un-conjugated |
| 別名 | Phosphatidylinositol-four-phosphate adapter protein 2; Serologically defined breast cancer antigen NY-BR-86; hFAPP2; PH domain-containing family A member 8; FAPP-2; FAPP2; Pleckstrin homology domain-containing family A member 8; Phosphoinositol 4-phosphate adapter protein 2 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96JA3 Human Pleckstrin homology domain-containing family A member 8 |
|---|---|
| 基因名称 | PLEKHA8 |
| 全名 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 |
| 生物功能 | Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 58 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG63516 anti-FAPP2 / PLEKHA8 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Placenta. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63516 anti-FAPP2 / PLEKHA8 antibody at 2.5 µg/ml dilution followed by AP-staining.
