ARG46152
anti-FAIM2 antibody
anti-FAIM2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FAIM2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FAIM2 |
| 抗原物种 | Human |
| 抗原 | A 16 amino acid synthetic peptide within the first 50 amino acids of human FAIM2. |
| 偶联标记 | Un-conjugated |
| 別名 | FAIM2; LFG; LFG2; NGP35; NMP35; TMBIM2; KIAA0950; LFG; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -202°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FAIM2 |
| 全名 | Fas apoptotic inhibitory molecule 2 |
| 背景介绍 | Predicted to enable calcium channel activity. Involved in regulation of neuron apoptotic process. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Located in Golgi membrane and membrane raft. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. [UniProt] |
| 细胞定位 | Cell membrane. [UniProt] |
| 预测分子量 | 35 kDa |
| 翻译后修饰 | Glycoprotein. [UniProt] |
