ARG54127
anti-FADD antibody
anti-FADD antibody for Immunoprecipitation,Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody
1
概述
| 产品描述 | Mouse Monoclonal antibody recognizes FADD |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | FADD |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human FADD protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
| 別名 | Mediator of receptor induced toxicity; MORT1; GIG3; FAS-associated death domain protein; Growth-inhibiting gene 3 protein; Protein FADD; FAS-associating death domain-containing protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.2% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q13158 Human FAS-associated death domain protein |
|---|---|
| 基因名称 | FADD |
| 全名 | Fas (TNFRSF6)-associated via death domain |
| 背景介绍 | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation.Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.Involved in interferon-mediated antiviral immune response,playing a role in the positive regulation of interferon signaling. |
| 生物功能 | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [UniProt] |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody |
| 预测分子量 | 23 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG54127 anti-FADD antibody WB image
Western blot: 20 µg of 293T and HeLa cell lysates stained with ARG54127 anti-FADD antibody at 1:1000 dilution.
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anti-FADD antibody
Application：WB
Sample：293T and HeLa
Sample Loading Amount：20 µg
Primary Antibody Dilution Factor：1:1000
Primary Antibody Incubation Time：overnight
Primary Antibody Incubation Temperature：4 ºC
