ARG64242
anti-FACT / SUPT16H antibody
anti-FACT / SUPT16H antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes FACT / SUPT16H |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Cow, Pig |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FACT / SUPT16H |
| 抗原物种 | Human |
| 抗原 | C-DLTNKEGKKPEEK |
| 偶联标记 | Un-conjugated |
| 別名 | Chromatin-specific transcription elongation factor 140 kDa subunit; FACTP140; FACT complex subunit SPT16; SPT16; FACTp140; CDC68; FACT 140 kDa subunit; Facilitates chromatin transcription complex subunit SPT16; SPT16/CDC68; hSPT16 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009] |
| 研究领域 | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 120 kDa |
| 翻译后修饰 | ADP-ribosylated. ADP-ribosylation by PARP1 is induced by genotoxic stress and correlates with dissociation of FACT from chromatin. |
检测图片 (1) Click the Picture to Zoom In
-
ARG64242 anti-FACT / SUPT16H antibody WB image
Western Blot: HeLa cell lysate (35 µg protein in RIPA buffer) stained with ARG64242 anti-FACT / SUPT16H antibody at 0.1 µg/ml dilution.
