ARG55026
anti-FACE1 / ZMPSTE24 antibody
anti-FACE1 / ZMPSTE24 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Cell Biology and Cellular Response antibody; Developmental Biology antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes FACE1 / ZMPSTE24 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | FACE1 / ZMPSTE24 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 400-430 (Center) of Human ZMPSTE24. |
| 偶联标记 | Un-conjugated |
| 別名 | CAAX prenyl protease 1 homolog; EC 3.4.24.84; STE24; Ste24p; HGPS; FACE-1; Farnesylated proteins-converting enzyme 1; FACE1; Prenyl protein-specific endoprotease 1; PRO1; Zinc metalloproteinase Ste24 homolog |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse cerebellum |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ZMPSTE24 |
| 全名 | zinc metallopeptidase STE24 |
| 背景介绍 | This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008] |
| 生物功能 | Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein |
| 研究领域 | Cell Biology and Cellular Response antibody; Developmental Biology antibody; Signaling Transduction antibody |
| 预测分子量 | 55 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG55026 anti-FACE1 / ZMPSTE24 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human cancer tissue stained with ARG55026 anti-FACE1 / ZMPSTE24 antibody.
-
ARG55026 anti-FACE1 / ZMPSTE24 antibody WB image
Western blot: Mouse cerebellum lysate stained with ARG55026 anti-FACE1 / ZMPSTE24 antibody.
