ARG45456
anti-F11 antibody
anti-F11 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes F11 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | F11 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human F11. |
| 偶联标记 | Un-conjugated |
| 別名 | F11; Coagulation Factor XI; FXI; Plasma Thromboplastin Antecedent; PTA; Coagualtion Factor XI; EC 3.4.21.27; EC 3.4.21 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 150 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | F11 |
| 全名 | Coagulation Factor XI |
| 背景介绍 | This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008] |
| 生物功能 | Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 70 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Zymogen. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45456 anti-F11 antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG45456 anti-F11 antibody at 5 μg/ml dilution.
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ARG45456 anti-F11 antibody WB image
Western blot: HCCP stained with ARG45456 anti-F11 antibody at 0.25 μg/ml dilution.
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ARG45456 anti-F11 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45456 anti-F11 antibody at 1 µg/10^6 cells dilution.
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ARG45456 anti-F11 antibody WB image
Western blot: Rat liver stained with ARG45456 anti-F11 antibody at 0.25 μg/ml dilution.
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ARG45456 anti-F11 antibody WB image
Western blot: Mouse liver stained with ARG45456 anti-F11 antibody at 0.25 μg/ml dilution.
