ARG67248
anti-Estrogen receptor beta antibody [SQab30366]
anti-Estrogen receptor beta antibody [SQab30366] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Monoclonal antibody [SQab30366] recognizes Estrogen receptor beta. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30366 |
| 同位型 | IgG |
| 靶点名称 | Estrogen receptor beta |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to Human Estrogen receptor beta. |
| 偶联标记 | Un-conjugated |
| 別名 | ESR2; Estrogen Receptor 2; ER-Beta; NR3A2; Nuclear Receptor Subfamily 3 Group A Member 2; Estrogen Receptor Beta; Erb; Oestrogen Receptor Beta; ESTRB; Estrogen Receptor 2 (ER Beta); Estrogen Receptor Beta 2; Estrogen Receptor Beta 4; ESR-BETA; ER Beta; ESRB; ODG8 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ESR2 |
| 全名 | Estrogen Receptor 2 |
| 背景介绍 | This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. [Uniprot] |
| 细胞定位 | Nucleus. [Uniprot] |
| 预测分子量 | 59 kDa |
| 翻译后修饰 | Phosphoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG67248 anti-Estrogen receptor beta antibody [SQab30366] IHC-P image
Immunohistochemistry: Human Breast stained with ARG67248 anti-Estrogen receptor beta antibody [SQab30366] at 1:100 dilution.
