ARG45352
anti-Eph receptor B6 antibody [9B17]
anti-Eph receptor B6 antibody [9B17] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
概述
| 产品描述 | Rat Monoclonal antibody [9B17] recognizes Eph receptor B6 |
|---|---|
| 反应物种 | Ms |
| 应用 | IHC-P |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 9B17 |
| 同位型 | IgG2 |
| 靶点名称 | Eph receptor B6 |
| 抗原物种 | Mouse |
| 抗原 | Recombinant Mouse Eph receptor B6. |
| 偶联标记 | Un-conjugated |
| 別名 | EPHB6; EPH Receptor B6; HEP; Tyrosine-Protein Kinase-Defective Receptor EPH-6; Ephrin Type-B Receptor 6; Human Kinase-Defective Eph-Family Receptor Protein; EC 2.7.10.1; EphB6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G/A chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EphB6 |
| 全名 | EPH Receptor B6 |
| 背景介绍 | This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| 生物功能 | Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 . [UniProt] |
| 细胞定位 | Cell membrane; Membrane; Secreted. [UniProt] |
| 预测分子量 | 110 kDa |
| 翻译后修饰 | Glycoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45352 anti-Eph receptor B6 antibody [9B17] IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45352 anti-Eph receptor B6 antibody [9B17].
