ARG58628
anti-Endothelin B Receptor antibody
anti-Endothelin B Receptor antibody for Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Endothelin B Receptor |
|---|---|
| 反应物种 | Hu |
| 应用 | IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Endothelin B Receptor |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human Endothelin B Receptor. |
| 偶联标记 | Un-conjugated |
| 別名 | HSCR; WS4A; HSCR2; ETB1; Endothelin receptor non-selective type; ETRB; ETB; ET-B; ET-BR; Endothelin B receptor; ABCDS; ETBR |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | 293T | ||||||
| 实际分子量 | ~ 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EDNRB |
| 全名 | endothelin receptor type B |
| 背景介绍 | The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
| 生物功能 | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. [UniProt] |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG58628 anti-Endothelin B Receptor antibody WB image
Western blot: 293T cell lysate stained with ARG58628 anti-Endothelin B Receptor antibody.
