ARG58606
anti-EXT2 antibody
anti-EXT2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
参考文献2
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EXT2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Bov |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EXT2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide between aa. 182-209 of Human EXT2. |
| 偶联标记 | Un-conjugated |
| 別名 | Multiple exostoses protein 2; SOTV; Putative tumor suppressor protein EXT2; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; EC 2.4.1.225; EC 2.4.1.224; Exostosin-2 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | T47D |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EXT2 |
| 全名 | exostosin glycosyltransferase 2 |
| 背景介绍 | This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus. [UniProt] |
| 预测分子量 | 82 kDa |
检测图片 (3) Click the Picture to Zoom In
-
ARG58606 anti-EXT2 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human brain tissue stained with ARG58606 anti-EXT2 antibody.
-
ARG58606 anti-EXT2 antibody WB image
Western blot: 35 µg of T47D cell lysate stained with ARG58606 anti-EXT2 antibody at 1:1000 dilution.
-
ARG58606 anti-EXT2 antibody FACS image
Flow Cytometry: HeLa cells stained with ARG58606 anti-EXT2 antibody (bottom histogram) or without primary antibody as control (top histogram), followed by incubation with FITC labelled secondary antibody.
文献引用
Diagnostic Immunostaining of Renal Biopsies: An Overview of Markers for Glomerular Diseases
IHC-P / Human
Glomerular Exostosin-Positivity is Associated With Disease Activity and Outcomes in Patients With Membranous Lupus Nephritis
IHC-P / Human
