ARG58644
anti-EXT1 antibody
anti-EXT1 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EXT1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EXT1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 467-746 of Human EXT1 (NP_000118.2). |
| 偶联标记 | Un-conjugated |
| 別名 | TRPS2; Putative tumor suppressor protein EXT1; LGCR; TTV; EC 2.4.1.224; EXT; Multiple exostoses protein 1; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; LGS; EC 2.4.1.225; Exostosin-1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | PC-3 | ||||||
| 实际分子量 | 88 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EXT1 |
| 全名 | exostosin glycosyltransferase 1 |
| 背景介绍 | This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq, Jul 2008] |
| 生物功能 | Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane, Single-pass type II membrane protein, Golgi apparatus membrane. [UniProt] |
| 预测分子量 | 86 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58644 anti-EXT1 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG58644 anti-EXT1 antibody.
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ARG58644 anti-EXT1 antibody WB image
Western blot: 25 µg of PC-3 cell lysate stained with ARG58644 anti-EXT1 antibody at 1:1000 dilution.
