ARG45884
anti-EVC2 / Limbin antibody
anti-EVC2 / Limbin antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EVC2 / Limbin |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EVC2 / Limbin |
| 抗原物种 | Mouse |
| 抗原 | Recombinant protein containing to mouse EVC2 / Limbin. |
| 偶联标记 | Un-conjugated |
| 別名 | EvC Ciliary Complex Subunit 2; Ellis-van Creveld syndrome protein 2; WAD; Limbin; EVC2; LBN |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 153 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EVC2 |
| 全名 | EvC Ciliary Complex Subunit 2 |
| 背景介绍 | This gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as well as in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomal recessive skeletal dysplasia that is also known as chondroectodermal dysplasia. Mutations in this gene also cause acrofacial dysostosis Weyers type, also referred to as Curry-Hall syndrome, a disease that combines limb and facial abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
| 生物功能 | Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. [UniProt] |
| 细胞定位 | Cell membrane; Cell projection; Cilium; Cytoplasm; Cytoskeleton. [UniProt] |
| 预测分子量 | 138 kDa |
| 翻译后修饰 | Glycoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45884 anti-EVC2 / Limbin antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG45884 anti-EVC2 / Limbin antibody at 2 μg/ml dilution.
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ARG45884 anti-EVC2 / Limbin antibody WB image
Western blot: PC-12 stained with ARG45884 anti-EVC2 / Limbin antibody at 0.5 μg/ml dilution.
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ARG45884 anti-EVC2 / Limbin antibody WB image
Western blot: NIH/3T3 stained with ARG45884 anti-EVC2 / Limbin antibody at 0.5 μg/ml dilution.
