概述

产品描述	Rabbit Polyclonal antibody recognizes ETS2
反应物种	Hu, Ms, Rat
应用	ICC/IF, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ETS2
抗原物种	Human
抗原	Recombinant fusion protein corresponding to aa. 160-350 of Human ETS2 (NP_005230.1).
偶联标记	Un-conjugated
別名	Protein C-ets-2; ETS2IT1

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	53 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 2114 Human ETS2 GeneID: 23872 Mouse ETS2 Swiss-port # P15036 Human Protein C-ets-2 Swiss-port # P15037 Mouse Protein C-ets-2
基因名称	ETS2
全名	v-ets avian erythroblastosis virus E26 oncogene homolog 2
背景介绍	This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
生物功能	Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription. [UniProt]
细胞定位	Nucleus. [UniProt]
预测分子量	53 kDa
翻译后修饰	Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation. [UniProt]

检测图片 (1) Click the Picture to Zoom In