ARG58608
anti-ETS2 antibody
anti-ETS2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ETS2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Bov |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ETS2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide between aa. 146-173 of Human ETS2. |
| 偶联标记 | Un-conjugated |
| 別名 | Protein C-ets-2; ETS2IT1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | MCF7 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ETS2 |
| 全名 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| 背景介绍 | This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
| 生物功能 | Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 53 kDa |
| 翻译后修饰 | Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG58608 anti-ETS2 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human brain tissue stained with ARG58608 anti-ETS2 antibody.
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ARG58608 anti-ETS2 antibody WB image
Western blot: 35 µg of MCF7 cell lysate stained with ARG58608 anti-ETS2 antibody.
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ARG58608 anti-ETS2 antibody FACS image
Flow Cytometry: MCF7 cells stained with ARG58608 anti-ETS2 antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
