ARG58613
anti-ETS1 antibody
anti-ETS1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ETS1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog, Goat, Gpig, Hrs, Rb, Zfsh |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ETS1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminal region of Human ETS1. (within the following sequence: TFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMN) |
| 偶联标记 | Un-conjugated |
| 別名 | p54; c-ets-1; Protein C-ets-1; ETS-1; EWSR2 |
应用说明
| 预测反应性说明 | Predicted homology based on immunogen sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 84% | ||||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ETS1 |
| 全名 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| 背景介绍 | This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| 生物功能 | Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. [UniProt] |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2; which inhibits transcriptional activity. Ubiquitinated; which induces proteasomal degradation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG58613 anti-ETS1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human Pancrease stained with ARG58613 anti-ETS1 antibody.
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ARG58613 anti-ETS1 antibody WB image
Western blot: HepG2 cell lysate stained with ARG58613 anti-ETS1 antibody at 1 µg/ml dilution.
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ARG58613 anti-ETS1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney stained with ARG58613 anti-ETS1 antibody.
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ARG58613 anti-ETS1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human alveolar cell stained with ARG58613 anti-ETS1 antibody at 4 - 8 µg/ml dilution. Magnification: 400X.
