ARG44251
anti-ERCC1 antibody
anti-ERCC1 antibody for ICC/IF and Human
Cancer antibody; Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes ERCC1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | ICC/IF |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ERCC1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the internal region of Human ERCC1 (QVDVKDPQQALKE) |
| 偶联标记 | Un-conjugated |
| 別名 | DNA excision repair protein ERCC-1; RAD10; COFS4; UV20 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P07992 Human DNA excision repair protein ERCC-1 |
|---|---|
| 基因名称 | ERCC1 |
| 全名 | excision repair cross-complementation group 1 |
| 背景介绍 | Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.Responsible,in conjunction with SLX4,for the first step in the repair of interstrand cross-links (ICL).Participates in the processing of anaphase bridge-generating DNA structures,which consist in incompletely processed DNA lesions arising during S or G2 phase,and can result in cytokinesis failure.Also required for homology-directed repair (HDR) of DNA double-strand breaks,in conjunction with SLX4. |
| 生物功能 | Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. [UniProt] |
| 细胞定位 | Isoform 1: Nucleus. Isoform 2: Cytoplasm. Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. |
| 研究领域 | Cancer antibody; Gene Regulation antibody |
检测图片 (2) Click the Picture to Zoom In
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ARG44251 anti-ERCC1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44251 anti-ERCC1 antibody at 10µg/ml dilution.
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ARG44251 anti-ERCC1 antibody ICC/IF image
Immunofluorescence: A431 stained with ARG44251 anti-ERCC1 antibody at 10µg/ml dilution.
