ARG45647
anti-ERAP2 antibody
anti-ERAP2 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ERAP2 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ERAP2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human ERAP2. |
| 偶联标记 | Un-conjugated |
| 別名 | ERAP2; Endoplasmic Reticulum Aminopeptidase 2; L-RAP; LRAP; Leukocyte-Derived Arginine Aminopeptidase; EC 3.4.11.-; EC 3.4.11.3 47; EC 3.4.11 47 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6P179 Human Endoplasmic reticulum aminopeptidase 2 |
|---|---|
| 基因名称 | ERAP2 |
| 全名 | Endoplasmic Reticulum Aminopeptidase 2 |
| 背景介绍 | This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5. [provided by RefSeq, Jul 2016] |
| 生物功能 | Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys. [UniProt] |
| 细胞定位 | Endoplasmic reticulum; Membrane. [UniProt] |
| 预测分子量 | 110 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG45647 anti-ERAP2 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45647 anti-ERAP2 antibody at 2 μg/ml dilution.
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ARG45647 anti-ERAP2 antibody WB image
Western blot: CACO-2 stained with ARG45647 anti-ERAP2 antibody at 0.5 μg/ml dilution.
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ARG45647 anti-ERAP2 antibody FACS image
Flow Cytometry: HL-60 stained with ARG45647 anti-ERAP2 antibody at 1 µg/10^6 cells dilution.
