ARG42844
anti-EPS15R antibody
anti-EPS15R antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EPS15R |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EPS15R |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 475-754 of Human EPS15R (NP_001245304.1). |
| 偶联标记 | Un-conjugated |
| 別名 | EPS15R; Eps15R; Epidermal growth factor receptor substrate 15-like 1; Eps15-related protein |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa | ||||
| 实际分子量 | ~ 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UBC2 Human Epidermal growth factor receptor substrate 15-like 1 |
|---|---|
| 基因名称 | EPS15L1 |
| 全名 | epidermal growth factor receptor pathway substrate 15-like 1 |
| 生物功能 | Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. [UniProt] |
| 细胞定位 | Cell membrane; Peripheral membrane protein. Nucleus. Membrane, coated pit. Note=Localized to plasma membrane coated pits. [UniProt] |
| 预测分子量 | 94 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues by EGFR. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42844 anti-EPS15R antibody WB image
Western blot: 25 µg of HeLa cell lysate stained with ARG42844 anti-EPS15R antibody at 1:1000 dilution.
