ARG59188
anti-EOMES / TBR2 antibody
anti-EOMES / TBR2 antibody for Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EOMES / TBR2 |
|---|---|
| 反应物种 | Ms, Rat |
| 预测物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EOMES / TBR2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to T310-D532 of Human EOMES / TBR2. |
| 偶联标记 | Un-conjugated |
| 別名 | TBR-2; T-box brain protein 2; Eomesodermin homolog; TBR2; T-brain-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EOMES |
| 全名 | eomesodermin |
| 背景介绍 | This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| 生物功能 | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 73 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59188 anti-EOMES / TBR2 antibody WB image
Western blot: 50 µg of samples under reducing conditions. Rat spleen, Rat thymus, Mouse spleen and Mouse thymus lysates stained with ARG59188 anti-EOMES / TBR2 antibody at 0.5 µg/ml, overnight at 4°C.
