ARG63814
anti-ENPP1 / PC1 antibody
anti-ENPP1 / PC1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes ENPP1 / PC1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat |
| 应用 | IHC-P |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ENPP1 / PC1 |
| 抗原物种 | Human |
| 抗原 | C-KTHLPTFSQED |
| 偶联标记 | Un-conjugated |
| 別名 | Membrane component chromosome 6 surface marker 1; EC 3.6.1.9; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1; NPPase; PDNP1; PC-1; NPPS; NPP1; E-NPP 1; M6S1; Plasma-cell membrane glycoprotein PC-1; EC 3.1.4.1; COLED; PCA1; ARHR2; Phosphodiesterase I/nucleotide pyrophosphatase 1 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P22413 Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 |
|---|---|
| 背景介绍 | This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008] |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 105 kDa |
| 翻译后修饰 | Autophosphorylated as part of the catalytic cycle of phosphodiesterase/pyrophosphatase activity. N-glycosylated. A secreted form is produced through cleavage at Lys-103 by intracellular processing. |
检测图片 (1) Click the Picture to Zoom In
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ARG63814 anti-ENPP1 / PC1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid gland tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG63814 anti-ENPP1 / PC1 antibody at 8 µg/ml dilution followed by HRP-staining.
