ARG43031
anti-EML4 antibody
anti-EML4 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EML4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EML4 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 360-560 of Human EML4 (NP_061936.2). |
| 偶联标记 | Un-conjugated |
| 別名 | ELP120; ROPP120; C2orf2; Echinoderm microtubule-associated protein-like 4; EMAP-4; Ropp 120; EMAPL4; Restrictedly overexpressed proliferation-associated protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q3UMY5 Mouse Echinoderm microtubule-associated protein-like 4 Swiss-port # Q9HC35 Human Echinoderm microtubule-associated protein-like 4 |
|---|---|
| 基因名称 | EML4 |
| 全名 | echinoderm microtubule associated protein like 4 |
| 背景介绍 | This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015] |
| 生物功能 | May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. [UniProt] |
| 预测分子量 | 109 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG43031 anti-EML4 antibody ICC/IF image
Immunofluorescence: L929 cells stained with ARG43031 anti-EML4 antibody at 1:100 dilution.
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ARG43031 anti-EML4 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG43031 anti-EML4 antibody at 1:100 dilution.
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ARG43031 anti-EML4 antibody WB image
Western blot: 25 µg of HepG2 cell lysate stained with ARG43031 anti-EML4 antibody at 1:1000 dilution.
