ARG42013
anti-ELP3 / KAT9 antibody
anti-ELP3 / KAT9 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ELP3 / KAT9 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ELP3 / KAT9 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 358-547 of Human ELP3 / KAT9 (NP_060561.3). |
| 偶联标记 | Un-conjugated |
| 別名 | KAT9; Elongator complex protein 3; hELP3; EC 2.3.1.48 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse kidney | ||||||
| 实际分子量 | ~ 62 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ELP3 |
| 全名 | elongator acetyltransferase complex subunit 3 |
| 背景介绍 | ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009] |
| 生物功能 | Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin. May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm. Isoform 1: Nucleus. Isoform 2: Cytoplasm. Nucleus. [UniProt] |
| 预测分子量 | 62 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG42013 anti-ELP3 / KAT9 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse cerebellum tissue stained with ARG42013 anti-ELP3 / KAT9 antibody at 1:100 dilution.
-
ARG42013 anti-ELP3 / KAT9 antibody WB image
Western blot: 25 µg of Mouse kidney lysate stained with ARG42013 anti-ELP3 / KAT9 antibody at 1:1000 dilution.
