概述

产品描述	Rabbit Polyclonal antibody recognizes ELP3 / KAT9
反应物种	Hu, Ms, Rat
应用	ICC/IF, IP, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	ELP3 / KAT9
抗原物种	Human
抗原	Synthetic peptide of Human ELP3 / KAT9.
偶联标记	Un-conjugated
別名	KAT9; Elongator complex protein 3; hELP3; EC 2.3.1.48

应用说明

应用建议	应用 推荐稀释比 ICC/IF 1:50 - 1:200 IP 1:50 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	HeLa
实际分子量	~ 62 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 55140 Human ELP3 GeneID: 74195 Mouse ELP3 Swiss-port # Q9CZX0 Mouse Elongator complex protein 3 Swiss-port # Q9H9T3 Human Elongator complex protein 3
基因名称	ELP3
全名	elongator acetyltransferase complex subunit 3
背景介绍	ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]
生物功能	Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in acetylation of alpha-tubulin. May also have a methyltransferase activity. Involved in cell migration. Involved in neurogenesis. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (By similarity). [UniProt]
细胞定位	Cytoplasm. Isoform 1: Nucleus. Isoform 2: Cytoplasm. Nucleus. [UniProt]
预测分子量	62 kDa

检测图片 (1) Click the Picture to Zoom In