ARG56319
anti-ELAVL3 / HUC antibody
anti-ELAVL3 / HUC antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ELAVL3 / HUC |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ELAVL3 / HUC |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human ELAVL3 / HUC |
| 偶联标记 | Un-conjugated |
| 別名 | Paraneoplastic limbic encephalitis antigen 21; HUCL; HuC; Hu-antigen C; PLE21; ELAV-like protein 3; Paraneoplastic cerebellar degeneration-associated antigen; HUC |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse spinal cord |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ELAVL3 |
| 全名 | ELAV like neuron-specific RNA binding protein 3 |
| 背景介绍 | A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. May also bind poly-A tracts via RRM 3 (By similarity). May be involved in neuronal differentiation and maintenance. [UniProt] |
| 预测分子量 | 40 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG56319 anti-ELAVL3 / HUC antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG56319 anti-ELAVL3 / HUC antibody at 1:200 dilution.
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ARG56319 anti-ELAVL3 / HUC antibody WB image
Western blot: Mouse spinal cord lysate stained with ARG56319 anti-ELAVL3 / HUC antibody.
