ARG56328
anti-EIF2S3 antibody
anti-EIF2S3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EIF2S3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EIF2S3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human EIF2S3 |
| 偶联标记 | Un-conjugated |
| 別名 | Eukaryotic translation initiation factor 2 subunit 3; EIF2G; EIF2; eIF-2-gamma X; Eukaryotic translation initiation factor 2 subunit gamma X; eIF-2gX; EIF2gamma; eIF-2gA |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HL-60 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P41091 Human Eukaryotic translation initiation factor 2 subunit 3 |
|---|---|
| 基因名称 | EIF2S3 |
| 全名 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| 背景介绍 | The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010] |
| 生物功能 | eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG56328 anti-EIF2S3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG56328 anti-EIF2S3 antibody at 1:100 dilution.
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ARG56328 anti-EIF2S3 antibody WB image
Western blot: HL-60 cell lysate stained with ARG56328 anti-EIF2S3 antibody.
