概述

产品描述	Rabbit Polyclonal antibody recognizes EGR2.
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	EGR2
抗原物种	Human
抗原	Synthetic peptide derived from human EGR2
偶联标记	Un-conjugated
Protein Full name	E3 SUMO-protein ligase EGR2
別名	AT591; CMT1D; CMT4E; KROX20

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 114090 Rat EGR2 GeneID: 13654 Mouse EGR2 GeneID: 1959 Human EGR2 Swiss-port # P08152 Mouse E3 SUMO-protein ligase EGR2 Swiss-port # P11161 Human E3 SUMO-protein ligase EGR2 Swiss-port # P51774 Rat E3 SUMO-protein ligase EGR2 More
基因名称	EGR2
全名	early growth response 2
背景介绍	The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
生物功能	Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. [UniProt]

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