ARG44817
anti-EDA2R / XEDAR antibody
anti-EDA2R / XEDAR antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes EDA2R / XEDAR |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | EDA2R / XEDAR |
| 抗原物种 | Human |
| 抗原表位 | DKTAKEESLF PVPPSKETSA ESQVSENIFQ TQPLNPILED DCSSTSGFPT QESFTMASCT SESHSHWVHS |
| 偶联标记 | Un-conjugated |
| 別名 | EDA2R; Ectodysplasin A2 Receptor; TNFRSF27; XEDAR; EDA-A2R; EDAA2R; Tumor Necrosis Factor Receptor Superfamily Member 27; X-Linked Ectodysplasin-A2 Receptor; X-Linked EDA Receptor; EDA-A2 Receptor; Tumor Necrosis Factor Receptor Superfamily Member XEDAR |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9HAV5 Human Tumor necrosis factor receptor superfamily member 27 |
|---|---|
| 基因名称 | EDA2R |
| 全名 | Ectodysplasin A2 Receptor |
| 背景介绍 | The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016] |
| 生物功能 | Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6. [Uniprot] |
| 细胞定位 | Membrane. [Uniprot] |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
-
ARG44817 anti-EDA2R/XEDAR antibody IHC-P image
Immunohistochemistry: Human kidney stained with ARG44817 anti-EDA2R/XEDAR antibody at 5 µg/mL dilution.
