ARG57765
anti-EDA antibody
anti-EDA antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EDA |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EDA |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human EDA. |
| 偶联标记 | Un-conjugated |
| 別名 | Ectodermal dysplasia protein; EDA-A1; EDA protein; ED1-A2; EDA-A2; ECTD1; Ectodysplasin-A; HED1; XHED; HED; STHAGX1; ED1; EDA1; EDA2; ODT1; XLHED; ED1-A1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EDA |
| 全名 | ectodysplasin A |
| 背景介绍 | The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR. [UniProt] |
| 细胞定位 | Cell membrane, Single-pass type II membrane protein, Secreted. [UniProt] |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | N-glycosylated. Processing by furin produces a secreted form. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG57765 anti-EDA antibody WB image
Western blot: 25 µg of HepG2 cell lysate stained with ARG57765 anti-EDA antibody at 1:400 dilution.
