ARG45732
anti-ECSIT antibody
anti-ECSIT antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ECSIT |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ECSIT |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human ECSIT. |
| 偶联标记 | Un-conjugated |
| 別名 | ECSIT; ECSIT Signaling Integrator; SITPEC; Evolutionarily Conserved Signaling Intermediate In Toll Pathway, Mitochondrial; ECSIT Signalling Integrator; Likely Ortholog Of Mouse Signaling Intermediate In Toll Pathway Evolutionarily Conserved; Signaling Intermediate In Toll Pathway Evolutionarily Conserved Ortholog (Mouse); ECSIT Homolog (Drosophila); Protein SITPEC; ECSIT Homolog |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 49 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9BQ95 Human Evolutionarily conserved signaling intermediate in Toll pathway, mitochond |
|---|---|
| 基因名称 | ECSIT |
| 全名 | ECSIT Signaling Integrator |
| 背景介绍 | Enables molecular adaptor activity. Involved in regulation of oxidoreductase activity; regulation of protein complex stability; and toll-like receptor 4 signaling pathway. Located in cytosol; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | UniProtKB/Swiss-Prot Summary for ECSIT Gene Adapter protein that plays a role in different signaling pathways including TLRs and IL-1 pathways or innate antiviral induction signaling. Plays a role in the activation of NF-kappa-B by forming a signal complex with TRAF6 and TAK1/MAP3K7 to activate TAK1/MAP3K7 leading to activation of IKKs. [UniProt] |
| 细胞定位 | Cytoplasm; Mitochondrion; Nucleus. [UniProt] |
| 预测分子量 | 49 kDa |
| 翻译后修饰 | Isopeptide bond; Ubl conjugation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
-
ARG45732 anti-ECSIT antibody IHC-P image
Immunohistochemistry: Human bladder adenosquamous carcinoma stained with ARG45732 anti-ECSIT antibody at 2 μg/ml dilution.
-
ARG45732 anti-ECSIT antibody ICC/IF image
Immunofluorescence: PC-3 stained with ARG45732 anti-ECSIT antibody at 5 μg/ml dilution.
-
ARG45732 anti-ECSIT antibody WB image
Western blot: PC-3 stained with ARG45732 anti-ECSIT antibody at 0.5 μg/ml dilution.
-
ARG45732 anti-ECSIT antibody FACS image
Flow Cytometry: HepG2 stained with ARG45732 anti-ECSIT antibody at 1 µg/10^6 cells dilution.
