ARG22756
anti-EBV LMP2A antibody [15F9]
anti-EBV LMP2A antibody [15F9] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and EBV
概述
| 产品描述 | Rat Monoclonal antibody [15F9] recognizes EBV LMP2A This antibody recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a Human herpesvirus, which is associated with conditions such as Hodgkinas disease and Burkittas Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. This antibody specifically recognizes LMP2A and does not cross react with LMP2B. |
|---|---|
| 反应物种 | EBV |
| 应用 | IHC-P, WB |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 15F9 |
| 同位型 | IgG1 |
| 靶点名称 | EBV LMP2A |
| 抗原物种 | Virus |
| 抗原 | Bacterial TrpE-LMP2A fusion protein |
| 偶联标记 | Un-conjugated |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% Sodium azide. |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
