ARG67183
anti-Dhh antibody
anti-Dhh antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Dhh |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Dhh |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein of human Dhh |
| 偶联标记 | Un-conjugated |
| 別名 | HHG-3; Desert Hedgehog Protein; MGC35145; Desert Hedgehog (Drosophila) Homolog; Desert Hedgehog; EC 3.1; GDXYM 3; SRXY7 3; GDMN 3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 44 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Dhh |
| 全名 | Desert Hedgehog Signaling Molecule |
| 背景介绍 | This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010] |
| 生物功能 | The C-terminal part of the desert hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity).[UniProt] |
| 细胞定位 | Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane, Secreted Cell membrane. [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG67183 anti-Dhh antibody WB image
Western blot: Mouse skeletal muscle and rat skeletal muscle stained with ARG67183 anti-Dhh antibody.
