ARG45122
anti-Dhh antibody [6A12]
anti-Dhh antibody [6A12] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
概述
| 产品描述 | Rat Monoclonal antibody recognizes Dhh |
|---|---|
| 反应物种 | Ms |
| 应用 | IHC-P |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 6A12 |
| 同位型 | IgG2 |
| 靶点名称 | Dhh |
| 抗原物种 | Mouse |
| 抗原 | Mouse recombinant dhh N-terminal fragment. |
| 偶联标记 | Un-conjugated |
| 別名 | DHH; Desert Hedgehog Signaling Molecule; HHG-3; Desert Hedgehog Protein; MGC35145; Desert Hedgehog (Drosophila) Homolog; Desert Hedgehog; EC 3.1.-.-; GDXYM; SRXY7; GDMN |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G/A chromatography |
| 缓冲液 | PBS |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DHH |
| 全名 | Desert Hedgehog Signaling Molecule |
| 背景介绍 | This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. [provided by RefSeq, May 2010] |
| 生物功能 | In Schwann cells, controls the development of the peripheral nerve sheath and the transition of mesenchymal cells to form the epithelium-like structure of the perineurial tube. [Uniprot] |
| 细胞定位 | Cell membrane; Endoplasmic reticulum; Golgi apparatus; Membrane; Secreted. [Uniprot] |
| 预测分子量 | 44 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG45122 anti-Dhh antibody [6A12] IHC-P image
Immunohistochemistry: Mouse Kidney stained with ARG45122 anti-Dhh antibody [6A12] at 1:400 dilution.
