anti-Desmoglein 3 antibody [5H10]

anti-Desmoglein 3 antibody [5H10] for Flow cytometry,ICC/IF,Western blot and Human


产品描述 Mouse Monoclonal antibody [5H10] recognizes Desmoglein 3
反应物种 Hu
宿主 Mouse
克隆 Monoclonal
克隆号 5H10
同位型 IgG1, kappa
靶点名称 Desmoglein 3
抗原物种 Human
抗原 Recombinant protein corresponding to the extracellular portion of Human Desmoglein 3.
偶联标记 Un-conjugated
別名 PVA; 130 kDa pemphigus vulgaris antigen; CDHF6; Cadherin family member 6; Desmoglein-3


应用 推荐稀释比
FACS0.5 - 1 µg/10^6 cells
ICC/IF1 - 5 µg/ml
WB0.5 - 1 µg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS, 0.05% Sodium azide and 0.1 mg/ml BSA.
抗菌剂 0.05% Sodium azide
稳定剂 0.1 mg/ml BSA
浓度 0.2 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 1830 Human DSG3

Swiss-port # P32926 Human Desmoglein-3

基因名称 DSG3
全名 desmoglein 3
背景介绍 Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008]
生物功能 Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]
细胞定位 Cell surface. [UniProt]
预测分子量 108 kDa