anti-Desmoglein 2 antibody

anti-Desmoglein 2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat


产品描述 Rabbit Polyclonal antibody recognizes Desmoglein 2
反应物种 Hu, Ms, Rat
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Desmoglein 2
抗原物种 Human
抗原 Synthetic peptide derived from Human Desmoglein 2.
偶联标记 Un-conjugated
別名 ARVD10; Desmoglein-2; ARVC10; CMD1BB; CDHF5; Cadherin family member 5; HDGC


应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 13511 Mouse DSG2

GeneID: 1829 Human DSG2

Swiss-port # O55111 Mouse Desmoglein-2

Swiss-port # Q14126 Human Desmoglein-2

基因名称 DSG2
全名 desmoglein 2
背景介绍 Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jul 2008]
生物功能 Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]
预测分子量 122 kDa