ARG45803
anti-Deptor antibody
anti-Deptor antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Deptor |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Deptor |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Deptor. |
| 偶联标记 | Un-conjugated |
| 別名 | DEPTOR; DEP domain containing MTOR-interacting protein; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; DEPDC6; DEP.6 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 48 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q570Y9 Mouse DEP domain-containing mTOR-interacting protein Swiss-port # Q8TB45 Human DEP domain-containing mTOR-interacting protein |
|---|---|
| 基因名称 | DEPTOR |
| 全名 | DEP domain containing MTOR-interacting protein |
| 背景介绍 | Enables phosphatidic acid binding activity and protein serine/threonine kinase inhibitor activity. Involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Is active in lysosomal membrane. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. [UniProt] |
| 细胞定位 | Lysosome; Membrane. [UniProt] |
| 预测分子量 | 46 kDa |
| 翻译后修饰 | Phosphorylated. Phosphorylation weakens interaction with MTOR within mTORC1 and mTORC2. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
-
ARG45803 anti-Deptor antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45803 anti-Deptor antibody at 2 μg/ml dilution.
-
ARG45803 anti-Deptor antibody WB image
Western blot: MCF-7 stained with ARG45803 anti-Deptor antibody at 0.5 μg/ml dilution.
-
ARG45803 anti-Deptor antibody FACS image
Flow Cytometry: MCF-7 stained with ARG45803 anti-Deptor antibody at 1 µg/10^6 cells dilution.
-
ARG45803 anti-Deptor antibody WB image
Western blot: Rat heart stained with ARG45803 anti-Deptor antibody at 0.5 μg/ml dilution.
-
ARG45803 anti-Deptor antibody WB image
Western blot: Mouse heart stained with ARG45803 anti-Deptor antibody at 0.5 μg/ml dilution.
