ARG43298
anti-Decorin antibody [DCN/3523]
anti-Decorin antibody [DCN/3523] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [DCN/3523] recognizes Decorin |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | DCN/3523 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | Decorin |
| 抗原物种 | Human |
| 抗原 | Recombinant partial protein corresponding to aa. 212-336 of Human Decorin. |
| 偶联标记 | Un-conjugated |
| 別名 | Bone proteoglycan II; PG40; PGII; CSCD; SLRR1B; PGS2; PG-S2; DSPG2; Decorin |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0) for 10-20 min, followed by cooling at RT. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS, 0.05% Sodium azide and 0.1 mg/ml BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DCN |
| 全名 | decorin |
| 背景介绍 | This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015] |
| 生物功能 | May affect the rate of fibrils formation. [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG43298 anti-Decorin antibody [DCN/3523] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human skin tissue. Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0) for 10-20 min, followed by cooling at RT. The tissue section was stained with ARG43298 anti-Decorin antibody [DCN/3523].
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ARG43298 anti-Decorin antibody [DCN/3523] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human prostate tissue. Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0) for 10-20 min, followed by cooling at RT. The tissue section was stained with ARG43298 anti-Decorin antibody [DCN/3523].
