ARG44309
anti-Dclre1c / Artemis antibody
anti-Dclre1c / Artemis antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Dclre1c / Artemis |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Dclre1c / Artemis |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide |
| 偶联标记 | Un-conjugated |
| 別名 | DCLRE1C; DNA Cross-Link Repair 1C; SNM1C; ARTEMIS; A-SCID; SCIDA |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified |
| 缓冲液 | PBS with 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DCLRE1C |
| 全名 | DNA Cross-Link Repair 1C |
| 背景介绍 | This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. |
| 生物功能 | Nuclease involved in DNA non-homologous end joining (NHEJ); required for double-strand break repair and V(D)J recombination. |
| 细胞定位 | Nucleus |
| 预测分子量 | 78 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG44309 anti-Dclre1c / Artemis antibody WB image
Western blot: Human testis lysate stained with ARG44309 anti-Dclre1c / Artemis antibody.
