ARG40021
anti-DYNC2H1 antibody
anti-DYNC2H1 antibody for Western blot and Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DYNC2H1 |
|---|---|
| 反应物种 | Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DYNC2H1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-250 of Human DYNC2H1 (NP_001073932.1). |
| 偶联标记 | Un-conjugated |
| 別名 | DNCH2; DYH1B; hDHC11; SRTD3; hdhc11; Dynein cytoplasmic heavy chain 2; SRPS2B; DHC1b; ATD3; Cytoplasmic dynein 2 heavy chain; Cytoplasmic dynein 2 heavy chain 1; Dynein heavy chain 11; DHC2; Dynein heavy chain isotype 1B |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Rat testis | ||||
| 实际分子量 | 493 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DYNC2H1 |
| 全名 | dynein, cytoplasmic 2, heavy chain 1 |
| 背景介绍 | This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010] |
| 生物功能 | May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. May play a role in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells (By similarity). [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton, cilium axoneme. Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Localizes to the apical cytoplasm (By similarity). According to PubMed:8666668, it localizes to Golgi apparatus, cytoplasmic vesicle and endoplasmic reticulum (PubMed:8666668). [UniProt] |
| 预测分子量 | 493 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40021 anti-DYNC2H1 antibody WB image
Western blot: 25 µg of Rat testis lysate stained with ARG40021 anti-DYNC2H1 antibody at 1:1000 dilution.
